Bad Bug Update 01

Posted by on Jan 6, 2012 in BAD BUG UPDATE

Bad Bug Update 01

The latest new scary bug to become antibiotic resistant is one we are all to familiar with, klebsiella pneumoniae, which is the bacteria  coupon  that IS useD for validation along with the spore geobacillus  stearothermophilus. This  new strain is equipped with a gene that enables them to produce an enzyme that disables antibiotics to include carbapenam antibiotics, the last line of defense for infections that don’t respond to other drugs.This enzyme is called the klebsiella pneumoniae  carbapenamase or  “KFC”.

This bug has been reported by hospitals in more than 20 states and  is spreading rapidly. It typically strikes the critically ill, and is fatal in 30-60% of the cases. Fortunately these drugs are almost exclusively in hospitals and have not  become community based yet.

The other bugs are motivated by the NDM-1 gene , which is a another  very adaptable gene that hitches onto many types of common germs and confers broad drug resistance, creating dangerous “superbugs” . So far the gene altered bacteria have been found in only three states, California, Massachusetts  and Illinois,   and confine themselves mainly  to gut and urinary track infections. It is believed that this altered gene emanated  from India and Pakistan. The gene is carried by bacteria that can spread hand to mouth, which makes sound  hygiene  practices mandatory.  Scientists believe that the ingredients are there for world wide transmission. The over use of antibiotics is being blamed for  allowing  these mutant genes to evolve. That,  conjunctive with the fact that there are no new “ last line of defense” drugs  far enough  along In the R&D pipeline to bring relief to an outbreak in the near future, makes this all too  scary.